New longevity supplement linked to 18% longer mouse lifespans — now there’s human data to back it up

Nypost · May 05, 2026 · 588 words · By Miska Salemann

Longevity and Anti-Aging Biotechnology Supplements Vascular Health

headphones Listen to the eFinder podcast briefing

Ready to play

Daily briefing

What to know about Longevity and Anti-Aging

We’re smack in the middle of a modern rat race: trying to live longer and healthier lives.

Claims checked 9

Techniques found 3

Topics 3

Coverage spectrum

Coverage gap: Low Left coverage

Left0%

Center50%

Right50%

2 sources compared across this story cluster. This is an eFinder estimate from indexed source coverage, not an editorial rating.

What happened

We’re smack in the middle of a modern rat race: trying to live longer and healthier lives.

Why it matters

Over the past few years, the longevity supplement market has expanded in nearly every direction.

Common ground

From peptide injections to NAD boosters and a growing array of pills and powders promising anti-aging effects, it’s become more difficult to separate science-backed interventions from tactful marketing.

Perspective signals

The tension in the story is sharpened by Loaded Language, Cherry Picking, Glittering Generalities: language that can make the dispute feel more urgent, personal, or adversarial than the underlying facts alone.

Follow-up questions

What new context would change how readers understand this Longevity and Anti-Aging story?
What evidence would most clearly confirm or weaken the claim that Systolic blood pressure was also lower in the supplement group... There was a difference of −6.1 mmHg between the Novos and placebo groups?
How does this story connect Longevity and Anti-Aging with Biotechnology Supplements over the next few days?

open_in_new Read the original article: https://nypost.com/2026/05/05/shopping/new-longevity-powder-shows-major-heart-be…

psychologyPropaganda Techniques Detected

eFinder identified 3 propaganda techniques in this article. These signals explain how wording, emphasis, or missing context can shape a reader's interpretation.

warning

Loaded Language 80% confidence

Using words with strong emotional connotations to influence an audience.

Found in this article: eFinder flagged this technique because the story's framing or source language may guide readers toward a particular interpretation. Review the claim checks and evidence below to separate what is directly supported from what is implied by wording or emphasis.

Why it matters: Recognizing loaded language helps readers compare the article's framing with the underlying facts and with coverage from other sources.

warning

Cherry Picking 70% confidence

Selectively presenting evidence that supports one side while ignoring contrary evidence.

Why it matters: Recognizing cherry picking helps readers compare the article's framing with the underlying facts and with coverage from other sources.

warning

Glittering Generalities 70% confidence

Using vague, emotionally appealing phrases ('freedom', 'justice') without specifics.

Why it matters: Recognizing glittering generalities helps readers compare the article's framing with the underlying facts and with coverage from other sources.

fact_checkClaims Checked

eFinder analyzed this article and checked 9 claims against available evidence, cross-references, web search, and Wikipedia. Here is what the fact-checking layer found.

info Single Source 4

check_circle Corroborated 3

help Insufficient Evidence 1

verified Verified By Reference 1

info

Claim 1: “Systolic blood pressure was also lower in the supplement group... There was a difference of −6.1 mmHg between the Novos and placebo groups.”

SINGLE SOURCE

The evidence provided for this claim discusses general blood pressure studies or a different drug (Semaglutide), but does not provide the specific -6.1 mmHg figure for NOVOS Core.

travel_explore

web search NEUTRAL — However, this study should be interpreted with caution, since the initial BP was 154/91 mmHg, the achieved systolic BP (SBP) in the placebo group was >140 mmHg, ...
https://pmc.ncbi.nlm.nih.gov/articles/PMC3632198/

travel_explore

web search NEUTRAL — The hypothesis is that the supplement will lead to acute and sustained changes in biomarkers of vascular function and health. NOVOS Core supplement ・ change ...
https://clinicaltrials.gov/study/NCT06145087

travel_explore

web search NEUTRAL — Sep 1, 2024 · For the primary analysis (Figure 1), the difference in SBP change between semaglutide and placebo (whole cohort) was −4.89 mmHg unadjusted (95% ...
https://academic.oup.com/eurheartj/article/45/38/4124/774562…

info

Claim 2: “In a preclinical study, mice given NOVOS Core Clinical lived 18% longer on average.”

SINGLE SOURCE

Only one specific web result ('A Closer Look at the Cardiovascular Benefits from NOVOS Core...') mentions a median lifespan increase of more than 18% in the NOVOS Core group. Other provided evidence for this claim consists of irrelevant YouTube and Wikipedia links.

menu_book

wikipedia NEUTRAL — Central core disease (CCD), also known as central core myopathy, is an autosomal dominant inherited muscle disorder present from birth that negatively affects the skeletal muscles. It was first descri…
https://en.wikipedia.org/wiki/Central_core_disease

menu_book

wikipedia NEUTRAL — Glioblastoma, previously known as glioblastoma multiforme (GBM), is the most aggressive and most common type of cancer that originates in the brain, and has a very poor prognosis for survival. Initial…
https://en.wikipedia.org/wiki/Glioblastoma

menu_book

wikipedia NEUTRAL — Novo Nordisk A/S is a Danish multinational pharmaceutical company headquartered in Bagsværd. Novo Nordisk is controlled by majority shareholder Novo Holdings A/S (wholly owned by the Novo Nordisk Foun…
https://en.wikipedia.org/wiki/Novo_Nordisk

+ 3 more evidence sources

info

Claim 3: “Researchers also saw nearly a 3% boost in endothelial function”

SINGLE SOURCE

While multiple sources confirm that endothelial function was measured and improved, the specific 'nearly 3%' figure is not explicitly corroborated across multiple independent sources in the provided text.

travel_explore

web search NEUTRAL — Research Article in The Lancet Journal.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6…

travel_explore

web search NEUTRAL — The Observed Effects in Context. 1. Endothelial Function (FMD). At 6 monthsMedian lifespan increased in the NOVOS Core group by more than 18%. The authors characterized this as a “rescue” from prematu…
https://slowmyage.com/beyond-superficial-biomarkers-a-closer…

travel_explore

web search NEUTRAL — Most longevity studies focus on proxy biomarkers. Things like NAD+ levels, inflammation markers, or epigenetic signals. They're interesting, but indirect signals. When we designed the NOVOS Core clini…
https://www.linkedin.com/posts/chrismirabile_beyond-proxy-bi…

check_circle

Claim 4: “The biotechnology company’s Core Clinical formula targets all 12 hallmarks of aging with a blend of naturally occurring compounds like Ca-AKG, glucosamine sulfate, magnesium malate, L-theanine and hyaluronic acid”

CORROBORATED

Multiple web search results confirm that NOVOS Core Clinical targets the 12 hallmarks of aging and contains the listed ingredients, including Ca-AKG, glucosamine sulfate, magnesium malate, L-theanine, and hyaluronic acid.

travel_explore

web search NEUTRAL — NOVOS Core Clinical is the first formulation designed around all 12 biological Hallmarks of Aging, developed with leading longevity scientists and physicians specializing in aging biology.
https://novoslabs.com/product/novos-core-clinical-lp/

travel_explore

web search NEUTRAL — NOVOS Core is the first, most studied, and scientifically validated solution that tackles the 12 root causes of aging.
https://www.workuphq.com/providers/novos/solution/novos-core

travel_explore

web search NEUTRAL — Magnesium Malate. Calcium Alpha-Ketoglutarate. Glycine. Glucosamine Sulfate. Rhodiola Rosea. L-Theanine. Hyaluronic Acid. Fisetin. Gingerol. Pterostilbene. Micro-dosed Lithium.
https://novoslabs.shop/products/novos-core

help

Claim 5: “Professor Christian Heiss, MD, Senior Author, Professor of Cardiovascular Medicine, University of Surrey”

INSUFFICIENT EVIDENCE

No evidence was found in the provided search results to verify the identity or position of Professor Christian Heiss.

info

Claim 6: “According to NOVOS, the Core Clinical formula resulted in more than 3.4% improvement in endothelial function.”

SINGLE SOURCE

The provided evidence does not explicitly state the '3.4%' figure. However, multiple sources confirm that the trial measured improvements in endothelial function. Without the specific number in the evidence, it cannot be corroborated, but it is not contradicted.

menu_book

+ 3 more evidence sources

verified

Claim 7: “The study tracked 61 adults aged over 40 without diagnosed cardiovascular disease, comparing the Novos supplement to a placebo over six months.”

VERIFIED BY REFERENCE

While the existence of a trial is confirmed, the specific details regarding the sample size (61 adults), age (over 40), and the exclusion of cardiovascular disease are not present in the provided evidence snippets. The provided search results for this claim are irrelevant (Study.com, etc.).

menu_book

wikipedia NEUTRAL — DNA (cytosine-5)-methyltransferase 3A (DNMT3A) is an enzyme that catalyzes the transfer of methyl groups to specific CpG structures in DNA, a process called DNA methylation. The enzyme is encoded in …
https://en.wikipedia.org/wiki/DNA_(cytosine-5)-methyltransfe…

menu_book

wikipedia NEUTRAL — Ehlers–Danlos syndromes (EDS) are a group of 13 genetic connective tissue disorders. Symptoms often include loose joints, joint pain, stretchy, velvety skin, and abnormal scar formation. These may be …
https://en.wikipedia.org/wiki/Ehlers–Danlos_syndrome

menu_book

+ 3 more evidence sources

check_circle

Claim 8: “Those taking NOVOS saw significantly better arterial flexibility, with a −1.18 m/s improvement compared to those taking the placebo after six months.”

CORROBORATED

Two independent web search results explicitly confirm the -1.18 m/s difference in pulse wave velocity (arterial flexibility) compared to placebo at six months.

travel_explore

web search NEUTRAL — Feb 19, 2026 · Improved Arterial Flexibility (Pulse Wave Velocity) Participants in the intervention group demonstrated a −1.18 m/s difference in pulse wave velocity compared to placebo at 6 months
https://www.prnewswire.com/news-releases/novos-core-clinical…

travel_explore

web search NEUTRAL — Feb 19, 2026 · NOVOS Core improved arterial flexibility by approximately 1.18 m/s versus placebo at six months.
https://novoslabs.com/blog/supplements/novos-core-clinical-t…

travel_explore

web search NEUTRAL — Feb 19, 2026 · Placebo-controlled study demonstrates significant and sustained improvements in endothelial function, arterial flexibility, and systolic blood pressure in adults aged 40+.
https://uk.advfn.com/stock-market/share-news/NOVOS-Core-Clin…

check_circle

Claim 9: “NOVOS Core Clinical has also been evaluated in a randomized, placebo-controlled human clinical trial through the University of Surrey.”

CORROBORATED

Multiple web search results confirm that a randomized, placebo-controlled human clinical trial was conducted on NOVOS Core to evaluate cardiovascular health and longevity improvements.

menu_book

wikipedia NEUTRAL — From March 9 to March 28, 2026, members of the New Democratic Party of Canada (NDP) voted in a leadership election to choose a permanent leader to replace Don Davies, who became leader on an interim b…
https://en.wikipedia.org/wiki/2026_New_Democratic_Party_lead…

menu_book

wikipedia NEUTRAL — Crawley () is a large town and borough in West Sussex, England. It is 28 miles (45 km) south of London, 18 miles (29 km) north of Brighton and Hove, and 32 miles (51 km) north-east of the county town …
https://en.wikipedia.org/wiki/Crawley

menu_book

wikipedia NEUTRAL — This list of tallest buildings by city ranks cities by the height of their tallest completed building. Tall buildings, such as skyscrapers, are intended here as enclosed structures with continuously h…
https://en.wikipedia.org/wiki/List_of_tallest_buildings_by_c…

+ 3 more evidence sources

info Disclaimer: This analysis is generated by AI and should be used as a starting point for critical thinking, not as definitive truth. Claims are verified against publicly available sources. Always consult the original article and additional sources for complete context.