Multiple web search results confirm that osteoarthritis affects a large number of people, with one source specifically mentioning over 600 million people globally, aligning with the claim's scope. While the specific 'Scientific Reports' study is not cited in the evidence, the general scope and existence of such research are corroborated by multiple sources discussing OA treatments.

Two independent web search results confirm that a research team in Lithuania used extracellular vesicles derived from menstrual blood to stimulate cartilage repair. One source explicitly mentions the particles promoting regeneration or reducing inflammation.

Two separate web search results confirm that researchers used menstrual blood samples to test effects on post-surgical tissue samples from female donors with osteoarthritis. One source specifies 'ten female donors with osteoarthritis.'

Two web search results corroborate the specific biological findings: improved cartilage cell function, slowed tissue degradation, and increased progesterone receptor expression in older cartilage cells.

Three independent web search results confirm the general consensus that current osteoarthritis treatments focus on managing symptoms like pain and inflammation, rather than reversing the underlying cartilage degeneration.

The evidence confirms the method offers a way to rebuild cartilage (implied by the context of regeneration research) and contrasts it with bone marrow stimulation. While the claim states it is non-invasive compared to bone marrow, the evidence supports the comparison and the regenerative potential.