The web search results provide general definitions of 'approximately' and general Wikipedia information about US cities and Native Americans, but none of the provided evidence directly confirms the specific statistic that 'About 100,000 Americans have sickle cell disease (SCD), the most common inherited blood disorder in the US.' This specific numerical claim is not supported by the evidence provided.

The claim attributes the finding (10% of SCD patients in NY State, majority in NYC) to 'researchers at NYU School of Global Public Health.' While the evidence confirms the existence of NYU schools (NYU Law, NYU Stern, Wagner Graduate School of Public Service), none of the provided web search results or Wikipedia entries contain the specific finding or statistic regarding the distribution of SCD patients in New York State or NYC.

The claim specifies using 'data from 42,200 SCD hospitalizations in the state between 2009 and 2022' to assess specific outcomes. The web search results mention this exact study data ('Using data from 42,200 SCD hospitalizations in the state between 2009 and 2022, researchers assessed the length of hospital stays, total charges, severity of illness and risk of death'), but this specific detail is only found within the context of the search result snippet and is not corroborated by a second independent source or an authoritative reference.

The claim attributes the prevalence information (most prevalent among people of African descent) to 'Johns Hopkins Medicine.' While the evidence confirms the existence of Johns Hopkins Medicine in general terms, none of the provided web search results or Wikipedia entries contain this specific statement or statistic regarding the racial prevalence of the SCD mutation.

The claim provides specific data points (Central NY: 6.3 days, Hudson Valley: 6.2 days) from the NYU study. This specific comparative data is only present in the context of the search result snippet and is not corroborated by a second independent source or an authoritative reference.