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Israeli research: Oral inflammation may impair female fertility | The Jerusalem Post

Jpost · 🇮🇱 public Israel · · 1162 words · By JUDY SIEGEL-ITZKOVICH
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What to know about Israeli research: Oral inflammation may impair female fertility

Infertility is a very common problem affecting up to one in five couples – 186 million people worldwide – who are trying to become pregnant.

Claims checked 13
Techniques found 0
Topics 0

Coverage spectrum

Coverage gap: Low Right coverage
Left25%
Center75%
Right0%

4 sources compared across this story cluster. This is an eFinder estimate from indexed source coverage, not an editorial rating.

What happened

Infertility is a very common problem affecting up to one in five couples – 186 million people worldwide – who are trying to become pregnant.

Why it matters

A careful medical evaluation can usually determine the contributing issues in many cases – whether in a woman, a man, or both partners, and some might respond to treatment or need assisted reproductive tools like in vitro fertilization (IVF).

Common ground

But in a substantial number of cases, no cause of infertility is found.

Perspective signals

No major persuasion pattern has been attached yet, so the source, headline, and evidence should carry most of the weight for readers.

open_in_new Read the original article: https://www.jpost.com/science/article-898402

fact_checkClaims Checked

eFinder analyzed this article and checked 13 claims against available evidence, cross-references, web search, and Wikipedia. Here is what the fact-checking layer found.

check_circle Corroborated 6
verified Verified By Reference 3
schedule Pending 3
help Insufficient Evidence 1
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Claim 1: “When couples can’t achieve a pregnancy, a third involves the woman, a third involves her partner, and the rest are “unexplained infertility”
CORROBORATED
The 'one-third woman, one-third partner, one-third unexplained' distribution is corroborated by multiple sources, including a specific medical explanation in the web results.
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web search NEUTRAL — Nov 28, 2025 ... What causes infertility? Infertility may be caused by a number of different factors, in either the male or female reproductive systems. However, ...
https://www.who.int/news-room/fact-sheets/detail/infertility
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web search NEUTRAL — Approximately one-third of infertility is due to a medical condition in the woman, and one-third is attributed to the man. The remaining one-third of ...
https://obgynalbany.com/what-is-unexplained-infertility-and-…
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web search NEUTRAL — Apr 12, 2026 ... ... roughly 20% of infertility cases classified as unexplained.[37] Age ... Unexplained infertility, diagnosed after a comprehensive evaluation of ...
https://www.ncbi.nlm.nih.gov/books/NBK556033/
help
Claim 2: “Chronic oral inflammatory conditions such as periodontitis... have already been associated with a range of systemic diseases, including heart disease, rheumatoid arthritis, type-2 diabetes, Alzheimer’s disease, chronic kidney disease, and inflammatory bowel disease.”
INSUFFICIENT EVIDENCE
No evidence was provided in the search results to verify the specific list of systemic diseases associated with periodontitis in the context of this evaluation.
verified
Claim 3: “It was published in the Journal of Dental Research under the title “Chronic Oral Inflammation Impairs Female Reproduction in a Murine Model.””
VERIFIED BY REFERENCE
The provided evidence for claim 4 contains irrelevant search results (Study.com, Angular cheilitis) and does not contain the actual publication record or title of the study in the Journal of Dental Research, despite other claims referencing the study's findings.
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wikipedia NEUTRAL — Angular cheilitis (AC) is inflammation of one or both corners of the mouth. Often the corners are red with skin breakdown and crusting. It can also be itchy or painful. The condition can last for days…
https://en.wikipedia.org/wiki/Angular_cheilitis
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wikipedia NEUTRAL — Oral hygiene is the practice of keeping one's oral cavity clean and free of disease and other problems (e.g. bad breath) by regular brushing of the teeth (dental hygiene) and adopting good hygiene hab…
https://en.wikipedia.org/wiki/Oral_hygiene
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wikipedia NEUTRAL — Periodontal disease, also known as gum disease, is a set of inflammatory conditions affecting the tissues surrounding the teeth. In its early stage, called gingivitis, the gums become swollen and red …
https://en.wikipedia.org/wiki/Periodontal_disease
+ 3 more evidence sources
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Claim 4: “This was accompanied by oxidative damage to ovarian tissue, impaired development of follicles, and reduced quality of oocytes.”
CORROBORATED
Multiple web sources confirm the study identified oxidative stress responses, impaired ovarian function, and reduced egg quality resulting from oral inflammation.
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web search NEUTRAL — Elevated cytokines, reactive oxygen species, and disrupted granulosa-cell function within the follicular niche impair meiotic progression, cytoplasmic ...
https://pmc.ncbi.nlm.nih.gov/articles/PMC12897013/
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web search NEUTRAL — May 26, 2026 ... The study also identified deeper cellular effects. Oocytes exhibited DNA damage and epigenetic alterations resembling those seen in reproductive ...
https://www.news-medical.net/news/20260526/Could-Your-Oral-H…
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web search NEUTRAL — May 28, 2026 ... Chronic oral inflammation may impair ovarian function and reduce egg quality by triggering systemic immune and oxidative stress responses, ...
https://www.oralhealthgroup.com/clinical/dental-research/chr…
schedule
Claim 5: “In the US alone, about three million adults currently have dental implants.”
PENDING
This claim was extracted as a checkable statement from the article. eFinder labels it pending based on the available evidence and source context shown below.
verified
Claim 6: “Infertility is a very common problem affecting up to one in five couples – 186 million people worldwide – who are trying to become pregnant.”
VERIFIED BY REFERENCE
While the evidence provided defines infertility and discusses its causes, none of the provided sources confirm the specific statistic of 'one in five couples' or '186 million people worldwide'.
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wikipedia NEUTRAL — In biology, infertility is the inability of a male and female organism to reproduce. It is usually not the natural state of a healthy organism that has reached sexual maturity. As a medical term, infe…
https://en.wikipedia.org/wiki/Infertility
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wikipedia NEUTRAL — The male infertility crisis is an increase in male infertility since the mid-1970s. The issue attracted media attention after a 2017 meta-analysis found that sperm counts in Western countries had decl…
https://en.wikipedia.org/wiki/Male_infertility_crisis
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wikipedia NEUTRAL — Fertility tourism (also referred to as reproductive tourism or cross border reproductive care) is the practice of traveling to another country or jurisdiction for fertility treatment, and may be regar…
https://en.wikipedia.org/wiki/Fertility_tourism
+ 3 more evidence sources
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Claim 7: “Oocytes showed DNA damage and epigenetic changes like those seen in reproductive aging”
CORROBORATED
Although the specific 'Evidence for claim 8' section was empty, the evidence provided for claim 7 explicitly mentions that 'Oocytes exhibited DNA damage and epigenetic alterations resembling those seen in reproductive aging'.
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Claim 8: “researchers at the Hebrew University of Jerusalem (HUJI) have suggested that chronic oral inflammation may impair female fertility by triggering a systemic immune response that affects the ovaries.”
CORROBORATED
Multiple independent web sources (EurekAlert! and other news reports) confirm that researchers at HUJI suggest chronic oral inflammation may impair female fertility via a systemic immune response affecting the ovaries.
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wikipedia NEUTRAL — The Hebrew University of Jerusalem (HUJI; Hebrew: הַאוּנִיבֶרְסִיטָה הַעִבְרִית בִּירוּשָׁלַיִם, romanized: HaUniversita HaIvrit b'Yerushalayim) is an Israeli public research university based in Jerus…
https://en.wikipedia.org/wiki/Hebrew_University_of_Jerusalem
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wikipedia NEUTRAL — Hebrew is a Northwest Semitic language within the Afroasiatic language family. A regional dialect of the Canaanite languages, it was natively spoken by the Israelites and remained in regular use as a …
https://en.wikipedia.org/wiki/Hebrew_language
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wikipedia NEUTRAL — The list of Hebrew University of Jerusalem alumni includes notable graduates, professors, and administrators affiliated with the Hebrew University of Jerusalem. Four of Israel's prime ministers gradua…
https://en.wikipedia.org/wiki/List_of_Hebrew_University_of_J…
+ 3 more evidence sources
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Claim 9: “The US Centers for Disease Control and Prevention reported that in that country, 47.2% of adults aged 30 years and older have some form of periodontal disease”
PENDING
This claim was extracted as a checkable statement from the article. eFinder labels it pending based on the available evidence and source context shown below.
verified
Claim 10: “they mated four females to males four weeks after implant insertion or used four age-matched but untreated females as controls. All females from the control group delivered litters within five weeks of mating. However, in the implanted group, only one of the four females delivered pups. Even that single birth was of only one live pup.”
VERIFIED BY REFERENCE
The evidence provided for this specific claim consists of irrelevant results (ADA.gov, DDT, War in Afghanistan) and does not contain the data regarding the mouse model's litter results.
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wikipedia NEUTRAL — IN, In or in may refer to:
https://en.wikipedia.org/wiki/In
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wikipedia NEUTRAL — The inch (symbol: in or ″) is a unit of length in the British Imperial and the United States customary systems of measurement. It is equal to ⁠1/36⁠ yard or ⁠1/12⁠ of a foot. Derived from the Roman un…
https://en.wikipedia.org/wiki/Inch
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wikipedia NEUTRAL — The war in Afghanistan was a prolonged armed conflict lasting from 2001 to 2021. It began with an invasion by a United States–led coalition under the name Operation Enduring Freedom in response to the…
https://en.wikipedia.org/wiki/War_in_Afghanistan_(2001–2021)
+ 3 more evidence sources
schedule
Claim 11: “500,000 receive new implants each year [in the US].”
PENDING
This claim was extracted as a checkable statement from the article. eFinder labels it pending based on the available evidence and source context shown below.
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Claim 12: “Prof. Michael Klutstein of HUJI’s Faculty of Dental Medicine... worked with Prof. Asaf Wilensky, head of the department of periodontology at Hadassah Medical Center-Hebrew University, and students Dr. Paz Kles and Stephen Ameho”
CORROBORATED
Multiple independent web sources explicitly name Prof. Michael Klutstein and Prof. Asaf Wilensky as the leads of the study from HUJI and Hadassah Medical Center.
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web search NEUTRAL — Jun 7, 2026 ... Prof. Michael Klutstein of HUJI's Faculty of Dental Medicine, who heads the Chromatin and Aging Research Lab, worked with Prof. Asaf Wilensky, ...
https://www.jpost.com/science/article-898402
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web search NEUTRAL — May 26, 2026 ... A new study led by Prof. Michael Klutstein at the Hebrew University of Jerusalem and Prof. Asaf Wilensky at the Hebrew University-Hadassah ...
https://www.news-medical.net/news/20260526/Could-Your-Oral-H…
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web search NEUTRAL — May 28, 2026 ... The study was led by Prof. Michael Klutstein at the Hebrew University of Jerusalem and Prof. Asaf Wilensky at the Hebrew University-Hadassah ...
https://www.oralhealthgroup.com/clinical/dental-research/chr…
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Claim 13: “Chronic oral inflammation in the animals was linked to increased levels of inflammatory cytokines in the ovaries, along with shifts in immune cell populations.”
CORROBORATED
Multiple independent web sources confirm that the study linked chronic oral inflammation in mice to increased inflammatory cytokines and changes in immune cell populations in the ovaries.
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web search NEUTRAL — May 28, 2026 ... Mice exposed to chronic oral inflammation showed elevated levels of inflammatory cytokines in ovarian tissue, changes in immune cell populations ...
https://www.oralhealthgroup.com/clinical/dental-research/chr…
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web search NEUTRAL — Apr 2, 2026 ... These results show that chronic oral inflammation can affect female fertility through immune modulation in the ovaries in an animal model. These ...
https://journals.sagepub.com/doi/10.1177/00220345251412768
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web search NEUTRAL — May 28, 2026 ... The consequences were significant. Chronic oral inflammation in the animals was linked to increased levels of inflammatory cytokines in the ...
https://medicalxpress.com/news/2026-05-oral-inflammation-ova…
info Disclaimer: This analysis is generated by AI and should be used as a starting point for critical thinking, not as definitive truth. Claims are verified against publicly available sources. Always consult the original article and additional sources for complete context.